Miple ClinicThe suppressed hunger comes back
When the fullness signals the injections provided are gone, appetite returns with hunger hormone (ghrelin) elevated and satiety hormone (leptin) lowered.
Home › Post-Injection Care
After Wegovy · Mounjaro
If you stopped the injections
and are gaining weight again
It is not because your willpower is weak. The appetite the injections held down is coming back, and your metabolism has dropped by as much as the muscle you lost during weight loss. Now it is time to turn it on, not hold it down.
If you regain weight with muscle already lost, the next round of weight loss gets harder. The moment you start regaining is the fastest time to turn it around.
You can consult by remote consultation from anywhere in the country.
Why does it come back?
Three reasons the yo-yo effect happens
Muscle was lost along with fat
During rapid weight loss, muscle decreases as well. When muscle decreases, the energy you use even at rest, your basal metabolic rate, falls.
Your body goes into 'power-saving mode'
When weight drops, the body conserves energy to survive, and a 'weight set point' that tries to return to your old weight kicks in.
What remains after you stop
After stopping the injections, eating habits are what protect your weight
You must stop the medicine someday, but ingrained eating habits stay with you. Miple replenishes your staying power with herbal medicine and also sets up intermittent fasting and low-carb high-fat eating to fit your life. Read the diet guide →
Miple's post-injection care
We don't hold it down; we turn it back on
- Starting again with body compositionWith InBody, we check the muscle lost, remaining body fat, and swelling. We also check the injection you used and how long.
- A prescription that turns metabolism onWakes up mitochondria to raise energy use and regulates the causes of false hunger. If your energy has dropped, we consider GONG BI JIN YAK, which contains Gongjindan.
- Protecting muscleWe re-measure body composition every month and adjust the stage, diet and daily habits so that you keep your muscle mass.
- Coming down slowlyAs you near your goal, we lower the stage with a maintenance-stage prescription for a soft landing of 3 to 6 months or more. We help your body remember the new weight.
Suppression vs activation
The way they work is different
Wegovy · Mounjaro (GLP-1 injections)Miple herbal diet medicine
How it worksMimics satiety hormones to reduce appetiteLooks after metabolism and qi-blood circulation
What is managedDose and injection schedule adjusted with the prescribing doctorQi and blood replenished with a Gongjindan prescription; muscle mass checked with a monthly body composition test
After stoppingTiming of stopping is discussed with the prescribing doctorThe stage is lowered slowly with a maintenance-stage prescription
How it is takenWeekly injectionTwice a day, 1 stick pack
If you are on injection therapy, talk to your prescribing doctor before adding herbal medicine. Results may vary from person to person.
INBODY · ACTUAL RECORD131.2kg → 63.5kg
See the InBody result sheet →131.2kg → 63.5kg
14 months, −67.7kg
82% of the weight lost was body fat, and skeletal muscle mass stayed within the standard range.
Who this is for
- People regaining weight after stopping the injections
- People who want to stop because of the cost or side effects of the injections
- People who feel low on energy and tire easily after losing weight
- People who want a body that can maintain without injections
Frequently Asked Questions
After injections: your questions
Why do I gain weight again after stopping Wegovy or Mounjaro?
The injections work by mimicking satiety hormones to hold down appetite, so when you stop, the suppressed appetite returns. Muscle is lost along with weight, so your basal metabolic rate drops, and the body goes into an energy-saving 'power-saving mode', making it easier to gain even on the same amount of food.
I'm on injections. Can I take herbal medicine at the same time?
If you are on injection therapy, the rule is to talk to your prescribing doctor first. At Miple, we check the medication and dose you are using and your last injection date, then decide after the consultation whether you can take it.
I stopped the injections months ago and I've already gained the weight back.
It is not too late. We re-check your current muscle mass and body fat with a body composition test and start from the stage that turns your slowed metabolism back on. The aim is a body that can maintain without going back on injections.
Is herbal medicine after injections hard on the liver or kidneys?
We compared liver and kidney blood test values before and during herbal medicine use from 2022 to 2024. 52% stayed within the normal range for liver levels, and 38% saw levels that had been above the reference range come down. For kidney levels, 78% stayed within the normal range and 17% saw high levels come down. No case met the criteria for drug-induced liver injury. If you have a history of injection therapy, medication you are taking, or recent test results, we review them together at the consultation.
Isn't it slower than the injections?
In terms of speed of weight loss alone, injections can be faster. Miple focuses on protecting muscle, raising metabolism, and building a body that holds its weight even after you stop. We have the InBody record of a client who lost 67.7kg over 14 months from 131.2kg.
Here is how to send your first KakaoTalk message
Name: Height/weight: Biggest concern: Injection name · duration · last dose date: Medication/chronic conditions:
If you send us this, the doctor will review it and reply more precisely. It is fine to just ask for a consultation.
Turn the switch back on
If you tell us the medicine you used, how long, and your last dose date, we can consult more precisely.
Read more: Wegovy and Mounjaro vs herbal diet medicine → · What to tell us before a consultation if you are on injection therapy →